Description

Dynorphin (2-17) is a specific bioactive peptide fragment derived from the larger dynorphin A precursor. This compound is a valuable research tool for investigating the kappa opioid receptor (KOR) system and its role in neurological processes. It is primarily utilized by researchers and manufacturers in the fields of neuroscience, pharmacology, and drug discovery. The product is supplied under the CAS registry number 83608-80-4.

Application

• Neuroscience Research: A critical tool for studying the function and signaling pathways of the kappa opioid receptor (KOR) in the central nervous system.
• Pharmacological Studies: Used in in vitro and in vivo assays to investigate pain modulation, stress responses, and reward mechanisms.
• Biochemical Standard: Serves as a reference standard in analytical methods such as HPLC and mass spectrometry for quantifying dynorphin-related peptides.
• Drug Discovery & Development: Employed in high-throughput screening and structure-activity relationship (SAR) studies to develop novel analgesics and neurotherapeutics.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focused on neuropeptides and their physiological roles.

Basic Information

Product Name	Dynorphin (2-17)
CAS No.	83608-80-4
Molecular Formula	C85H138N24O21
Molecular Weight	1832.16 g/mol
Synonyms	Dynorphin A (2-17); Dynorphin A Fragment 2-17; [Des-Tyr1]-Dynorphin A; Dynorphin A (2-17) amide; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln (2-17 sequence); Leu-Enkephalin, Arg6, Arg7, Ile8, Arg9, Pro10, Lys11, Leu12, Lys13, Trp14, Asp15, Asn16, Gln17; Kappa opioid receptor peptide ligand.
EINECS	Contact for details

Quality Control

Our Dynorphin (2-17) is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.