Description

n-(Benzyloxycarbonyl)Glycyl-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its value lies in its role as a building block for creating more complex peptide-based compounds, enabling the study of enzyme interactions and biological pathways. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on protease inhibitor development and novel therapeutic peptide synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors, particularly for proteases like dipeptidyl peptidase.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic assays to study kinetic parameters and inhibition mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize peptide drug candidates for enhanced potency and stability.
• Peptide Library Synthesis: A valuable component in the combinatorial chemistry approach for generating diverse peptide libraries for high-throughput screening.

Basic Information

Product Name	n-(Benzyloxycarbonyl)Glycyl-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide
CAS No.	83575-46-6
Molecular Formula	C27H33N7O7
Molecular Weight	567.60 g/mol
Synonyms	Z-Gly-Pro-N5-Carbamoyl-N-(4-NO2-Phe)-Orn-NH2; Cbz-Gly-Pro-N5-Carbamoyl-N-(4-nitrophenyl)-L-ornithinamide; (S)-2-(((Benzyloxy)carbonyl)amino)-N-((S)-1-((S)-5-carbamoylamino-1-((4-nitrophenyl)amino)-1-oxopentan-2-yl)pyrrolidine-2-carbonyl)acetamide; Z-Gly-Pro-Nω-Carbamoyl-N-(4-Nitrophenyl)-L-Ornithinamide; Glycyl-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide, N-benzyloxycarbonyl-; DPP IV Inhibitor II (substrate analog); Peptide Intermediate 83575-46-6.
EINECS	Contact for details

Quality Control

Our n-(Benzyloxycarbonyl)Glycyl-L-Prolyl-N5-Carbamoyl-n-(4-Nitrophenyl)-L-Ornithinamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.