Description

3-Hydroxy-2-Imino-6-(4-Methylpiperazin-1-Yl)Pyrimidin-4-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-piperazine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel drug candidates targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Reagent: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor modulation.
• Preclinical Development: Integral in the scale-up synthesis of active pharmaceutical ingredients (APIs) for preclinical toxicology and pharmacology studies.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Item	Detail
Product Name	3-Hydroxy-2-Imino-6-(4-Methylpiperazin-1-Yl)Pyrimidin-4-Amine Dihydrochloride
CAS No.	83540-32-3
Molecular Formula	C9H16Cl2N6O
Molecular Weight	295.17 g/mol
Synonyms	6-(4-Methyl-1-piperazinyl)-2,4-diamino-5(2H)-pyrimidinone dihydrochloride; 2,4-Diamino-6-(4-methyl-1-piperazinyl)-5(2H)-pyrimidinone dihydrochloride; 6-(4-Methylpiperazin-1-yl)-2,4-diaminopyrimidin-5-ol dihydrochloride; 3-Hydroxy-2-imino-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine dihydrochloride; 5-Hydroxy-2,4-diamino-6-(4-methyl-1-piperazinyl)pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Imino-6-(4-Methylpiperazin-1-Yl)Pyrimidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.