Description

Cyclo(n-Methyltyrosylarginyl) CAS NO 83481-39-4 is a synthetic cyclic dipeptide derivative, also known as a diketopiperazine (DKP), formed from modified tyrosine and arginine residues. This compound is of significant interest in pharmaceutical research and development due to its potential as a constrained peptide scaffold for modulating biological activity and improving metabolic stability. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Used as a key building block in the synthesis of novel peptide-based therapeutics and peptidomimetics.
• Medicinal Chemistry Research: Serves as a constrained scaffold to study structure-activity relationships (SAR) and develop new bioactive compounds.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of related peptide products.
• Biochemical Tool Compound: Utilized in biochemical assays to investigate enzyme inhibition, receptor binding, or other biological pathways.
• Peptide Library Synthesis: Acts as a core structure for generating focused libraries in high-throughput screening for drug discovery.
• Academic Research: Applied in university and institutional labs for fundamental studies in organic synthesis and peptide chemistry.

Basic Information

Product Name	Cyclo(n-Methyltyrosylarginyl)
CAS No.	83481-39-4
Molecular Formula	C20H29N7O4
Molecular Weight	431.49 g/mol
Synonyms	Cyclo(N-Methyl-L-tyrosyl-L-arginyl); c(MeTyr-Arg); L-Arginyl-N-methyl-L-tyrosine cyclic (1→2)-peptide; 3-(4-Hydroxybenzyl)-6-(3-guanidinopropyl)-1-methylpiperazine-2,5-dione; Diketopiperazine derivative of N-Methyltyrosine and Arginine; Cyclo(MeTyr-Arg); (3S,6S)-3-(4-Hydroxybenzyl)-6-(4-amino-4-carbaminimidamidobutyl)-1-methylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclo(n-Methyltyrosylarginyl) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.