Description

Mono Q is a strong anion exchange chromatography medium, widely recognized for its high resolution and capacity in the purification of biomolecules. This product is essential for achieving high-purity separations of proteins, nucleic acids, and other charged biomolecules in research and industrial bioprocessing. It is a critical tool for downstream processing in the pharmaceutical, biotechnology, and life science research sectors, enabling efficient purification and analysis.

Application

• High-Resolution Protein Purification: Ideal for the final polishing step in the purification of therapeutic proteins, enzymes, and antibodies to remove trace impurities and aggregates.
• Nucleic Acid Separation: Used for the purification of plasmids, oligonucleotides, and other nucleic acids, ensuring high purity for molecular biology applications.
• Process Development & Scale-Up: Serves as a reliable medium for method development and scalable purification processes from laboratory to pilot and production scales.
• Analytical Chromatography: Employed in analytical columns for quality control, stability testing, and characterization of biomolecular charge variants.
• Vaccine Production: Applied in the downstream purification of viral vectors and vaccine components, meeting stringent regulatory requirements.
• Enzyme and Peptide Isolation: Effective for isolating and purifying specific enzymes, peptides, and other charged biological molecules from complex mixtures.

Basic Information

Product Name	Mono Q
CAS No.	83453-40-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mono Q Anion Exchanger; Q Sepharose Mono Q; Quaternary Aminoethyl Sepharose; Strong Anion Exchange Chromatography Medium; Mono Q 5/50 GL; Mono Q HR; QAE Sepharose; Anion Exchange Resin Q
EINECS	Contact for details

Quality Control

Our Mono Q chromatography medium is manufactured under a strict quality management system. Each lot is tested to ensure consistent performance characteristics such as binding capacity, particle size distribution, and flow properties. A comprehensive Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment to guarantee compliance with your process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15-25°C) in a dry place. For long-term storage of pre-packed columns, follow the manufacturer's recommended storage conditions, typically involving 20% ethanol solution to prevent microbial growth.

Specification

Item	Specification
Appearance	White suspension
Matrix	Highly cross-linked agarose
Particle Size	Contact for details
Ionic Capacity	Contact for details
Dynamic Binding Capacity (for BSA)	Contact for details
Maximum Pressure/Flow Rate	Contact for details
pH Stability	Contact for details
Storage Solution	20% Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.