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Desaminotyrosylfibrinopeptide A CAS NO 83437-30-3


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CAS No.:83437-30-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Desaminotyrosylfibrinopeptide A is a synthetic peptide fragment derived from fibrinogen, a key protein in the blood coagulation cascade. This compound is of significant value for biochemical research and pharmaceutical development, particularly in studies related to hemostasis, thrombosis, and platelet aggregation. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in cardiovascular and hematological research.

Application

  • Biochemical Research: Used as a standard or substrate in enzymatic assays to study thrombin activity and fibrin formation mechanisms.
  • Diagnostic Development: Serves as a critical component in the calibration and validation of diagnostic assays for coagulation disorders.
  • Pharmaceutical R&D: Employed in drug discovery programs targeting anticoagulant and antithrombotic therapies.
  • Platelet Function Studies: Utilized to investigate platelet activation and aggregation pathways in vitro.
  • Enzyme Kinetics: Acts as a specific peptide substrate for kinetic studies of serine proteases involved in the coagulation pathway.
  • Quality Control: Applied as a reference standard in the quality control of related biopharmaceutical products.

Basic Information

Product Name Desaminotyrosylfibrinopeptide A
CAS No. 83437-30-3
Molecular Formula C71H111N19O26S
Molecular Weight 1590.8 g/mol
Synonyms Des-Tyr-Fibrinopeptide A; Fibrinopeptide A (des-tyrosine); H-Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH; Desamino-Tyr-FPA; FPA (1-16) (des-Tyr); Fibrinopeptide A (1-16), des-Tyr-; Thrombin Substrate (Fibrinopeptide A derivative)
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Quality Control

Our Desaminotyrosylfibrinopeptide A is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Solubility Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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