Description

H-Tyr-Gly-Gly-Phe-Leu-Lys-Oh Acetate Salt is a synthetic hexapeptide acetate salt, a derivative of the endogenous opioid peptide Leu-enkephalin, known for its high purity and biological research relevance. This compound is critical for biochemical and pharmacological studies, particularly in neuroscience, due to its role in investigating opioid receptor interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuropeptide research and analgesic drug discovery.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of opioid receptor binding, activation, and downstream cellular effects.
• Pharmacological Studies: Serves as a key tool compound for investigating the structure-activity relationships (SAR) of enkephalin analogs and developing novel analgesic agents.
• Neuroscience Research: Applied in experimental models to study pain modulation, neurotransmitter release, and the role of the endogenous opioid system.
• Cell Signaling Assays: Utilized in vitro to stimulate and measure specific intracellular responses linked to G-protein coupled receptors (GPCRs).
• Pharmaceutical Development: Acts as a starting material or intermediate in the research phase for developing peptide-based therapeutics.
• Academic Research: Employed in university laboratories for teaching and advanced research projects in medicinal chemistry and neurobiology.

Basic Information

Product Name	H-Tyr-Gly-Gly-Phe-Leu-Lys-Oh Acetate Salt
CAS No.	83404-43-7
Molecular Formula	C37H55N7O9 • xC2H4O2
Molecular Weight	757.88 g/mol (Free base, C37H55N7O9)
Synonyms	Leu-Enkephalin, Lys6-Analog Acetate; H-Tyr-Gly-Gly-Phe-Leu-Lys-OH acetate; YGGFLK Acetate; Opioid Peptide (Leu-Enkephalin derivative) Acetate; L-Enkephalin, Lysine6-Acetate; Hexapeptide YGGFLK Acetate; [Lys6]-Leu-Enkephalin Acetate Salt
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Gly-Phe-Leu-Lys-Oh Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	1.0 - 3.0 eq
Peptide Content	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.