Description

Ofloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic, widely recognized for its potent bactericidal activity against a range of Gram-positive and Gram-negative pathogens. Its primary value lies in its effectiveness in treating serious bacterial infections, making it a critical active pharmaceutical ingredient (API) for global healthcare. This compound is essential for pharmaceutical manufacturers developing oral and topical formulations, including tablets, capsules, and ophthalmic solutions, to combat respiratory, urinary tract, skin, and eye infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of antibiotic medications.
• Oral Dosage Forms: Formulation into tablets and capsules for systemic treatment of bacterial infections.
• Ophthalmic Solutions: Key component in eye drops and ointments for treating bacterial conjunctivitis and corneal ulcers.
• Topical Creams/Ointments: Used in dermatological preparations for skin and soft tissue infections.
• Veterinary Medicine: Application in veterinary pharmaceuticals for treating bacterial diseases in animals.
• Intermediate Synthesis: Serves as a chemical intermediate in the research and synthesis of newer quinolone derivatives.

Basic Information

Product Name	Ofloxacin
CAS No.	83380-47-6
Molecular Formula	C18H20FN3O4
Molecular Weight	361.37 g/mol
Synonyms	Ofloxacin; (±)-Ofloxacin; DL-8280; Hoe 280; OFX; 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; Floxan; Tarivid; Exocin; Ocuflox
EINECS	Contact for details

Quality Control

Our Ofloxacin is manufactured under strict quality management systems, ensuring it meets high-purity standards suitable for pharmaceutical applications. Each batch is tested against rigorous specifications for identity, potency, and impurity profiles, aligning with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Optical Rotation	-0.10° to +0.10°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.