Description

Enkephalinamide, Met-Metazocine- CAS NO 83380-08-9 is a synthetic peptide derivative of the endogenous opioid peptide enkephalin, modified with a metazocine moiety. This compound is of significant interest in advanced pharmacological research due to its potential for high-affinity binding to opioid receptors, offering a valuable tool for studying pain modulation and neurological pathways. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in neurobiology, analgesic development, and receptor characterization studies.

Application

• Pharmacological Research: A key reference standard and active compound for investigating opioid receptor (MOR, DOR, KOR) interactions, binding affinity, and signal transduction mechanisms.
• Neuroscience Studies: Used in vitro and in vivo models to study the role of enkephalinergic systems in pain perception, reward, and mood regulation.
• Analgesic Drug Development: Serves as a lead compound or intermediate in the design and synthesis of novel, potent analgesic agents with potentially improved selectivity and reduced side-effect profiles.
• Biochemical Assays: Employed as a ligand in competitive binding assays, receptor autoradiography, and functional assays (e.g., GTPγS binding) to screen and evaluate new chemical entities.
• Structure-Activity Relationship (SAR) Studies: Provides a core scaffold for medicinal chemistry efforts aimed at understanding and optimizing the pharmacophore for opioid activity.

Basic Information

Product Name	Enkephalinamide, Met-Metazocine- CAS NO 83380-08-9
CAS No.	83380-08-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Met-Metazocine Enkephalinamide; [Metazocine(5)]-Enkephalinamide; Tyr-Gly-Gly-Phe-Met-Metazocine amide; Opioid peptide analog 83380-08-9; Met-Metazocine-Enkephalin; H-Tyr-Gly-Gly-Phe-Met-Metazocine-NH2; Enkephalin (Met-Metazocine) amide
EINECS	Contact for details

Quality Control

Our Enkephalinamide, Met-Metazocine- is produced under strict quality management protocols suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation and storage at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.