Description

Dynorphin B is a potent endogenous opioid peptide that plays a critical role in modulating pain perception, stress response, and neuroendocrine function. This high-purity peptide is essential for advanced life science research, enabling the study of κ-opioid receptor (KOR) signaling pathways and their implications in neurological disorders. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, analgesia, and addiction research. Dynorphin B CAS NO 83335-41-5 is supplied under stringent quality controls to ensure reliable and reproducible experimental results.

Application

• Neuroscience Research: Investigation of κ-opioid receptor (KOR) activation, signal transduction, and downstream effects in the central nervous system.
• Pain Mechanism Studies: Used as a research tool to understand the role of endogenous dynorphins in pain modulation and the development of novel analgesic targets.
• Psychiatric & Behavioral Research: Studying the peptide's involvement in stress responses, mood disorders, depression, and addictive behaviors.
• Neuroendocrine Research: Exploration of dynorphin's effects on hormone release and neuroendocrine regulation.
• Biomarker Development: Potential use in assay development for measuring dynorphin levels in biological samples.
• Reference Standard: Serves as a high-purity analytical standard for mass spectrometry, HPLC, and other qualitative/quantitative methods.
• Drug Discovery & Development: A key compound for screening and validating new therapeutic agents targeting the opioid receptor system.

Basic Information

Product Name	Dynorphin B
CAS No.	83335-41-5
Molecular Formula	C99H149N27O26
Molecular Weight	2147.4 g/mol
Synonyms	Leumorphin; Dynorphin B-29; Rimorphin; Dynorphin-29; Dynorphin B (1-13); Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr; [Leu5]-Enkephalin, Arg6, Arg7, Gln8, Phe9, Lys10, Val11, Val12, Thr13-; EINECS Not Available for peptides

Quality Control

Our Dynorphin B is manufactured and tested to meet the exacting standards required for critical research applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity verification and mass spectrometry for identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, ensuring compliance with internal quality specifications designed for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. Aliquot into single-use vials to minimize repeated freeze-thaw cycles and exposure to air, which can lead to oxidation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.