Description

1-Fluoronorhexestrol is a fluorinated synthetic estrogen derivative, distinguished by its specific structural modification which can impart unique biological and chemical properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly for creating novel therapeutic agents and biochemical probes. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors seeking to explore structure-activity relationships and develop new active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal or non-steroidal drug candidates for hormone-related therapies.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor (ER) binding affinity and selectivity.
• Agrochemical Development: Potential intermediate for creating new plant growth regulators or pesticides with specific activity profiles.
• Academic & Institutional R&D: Serves as a specialized reagent for synthetic organic chemistry and medicinal chemistry projects in university and corporate laboratories.
• Material Science Precursor: Can be utilized in the development of advanced organic materials and liquid crystals due to its rigid, fluorinated structure.

Basic Information

Product Name	1-Fluoronorhexestrol
CAS No.	83303-93-9
Molecular Formula	C20H23FO2
Molecular Weight	314.40 g/mol
Synonyms	1-Fluoro-1,2,3,4-tetrahydronorhexestrol; 1-Fluoro-1,2,3,4-tetrahydro-17α-ethynyl-18-nor-17β-estradiol; 1-Fluoro-17α-ethynyl-18-nor-17β-estradiol; 1-Fluoro-18-norhexestrol; NSC 112682; 1-Fluoronorhexoestrol; 1-Fluoro-Norhexestrol; 1-F-Norhexestrol
EINECS	Contact for details

Quality Control

Our 1-Fluoronorhexestrol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP standards for pharmaceutical intermediates, ensuring the product meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.