Description

3-Chloro-4-(Trifluoromethoxy)Benzaldehyde is a high-purity aromatic aldehyde building block characterized by its chloro and trifluoromethoxy substituents, which impart unique electronic and steric properties. This compound matters as a critical intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research, where its specific halogenated structure enables the fine-tuning of biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Employed in the creation of specialty polymers with tailored properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, condensations, and as a starting material for heterocyclic chemistry in academic and industrial research laboratories.
• Dye & Pigment Intermediate: Acts as a precursor in the manufacture of complex dyes and pigments, contributing to color fastness and performance.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethoxy)Benzaldehyde
CAS No.	83279-39-4
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	3-Chloro-4-(trifluoromethoxy)benzaldehyde; 4-Trifluoromethoxy-3-chlorobenzaldehyde; 3-Chloro-α,α,α-trifluoro-p-anisaldehyde; Benzaldehyde, 3-chloro-4-(trifluoromethoxy)-; 3-Chloro-4-trifluoromethoxybenzaldehyde; 83279-39-4; 3-Chloro-4-(trifluoromethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Trifluoromethoxy)Benzaldehyde is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.