Description

4,6-Dichloro-2-(2,5-Dimethoxyphenyl)Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty chemical libraries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other biological pathways where the pyrimidine core is essential.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive chlorine and methoxy groups for further functionalization.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Employed in university and institutional laboratories for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	4,6-Dichloro-2-(2,5-Dimethoxyphenyl)Pyrimidine
CAS No.	83217-68-9
Molecular Formula	C₁₂H₁₀Cl₂N₂O₂
Molecular Weight	285.13 g/mol
Synonyms	2-(2,5-Dimethoxyphenyl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(2,5-dimethoxyphenyl)pyrimidine; Pyrimidine, 4,6-dichloro-2-(2,5-dimethoxyphenyl)-; 83217-68-9; 4,6-Dichloro-2-(2,5-dimethoxy-phenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(2,5-Dimethoxyphenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, TSCA) ensures a reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and maintaining an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.