Description

6-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Pyrimidinone is a specialized heterocyclic organic compound featuring a pyrimidinone core substituted with a trifluoromethylphenyl group. This molecular structure makes it a valuable key intermediate and building block in advanced chemical synthesis, particularly for applications requiring specific electronic and steric properties. It is primarily utilized by pharmaceutical research and agrochemical development organizations engaged in the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidinone scaffold.
• Material Science: Investigated for the development of specialty polymers, liquid crystals, and organic electronic materials due to its unique aromatic and heterocyclic structure.
• Chemical Synthesis: Acts as a versatile reagent in organic chemistry for constructing complex heterocyclic systems and fluorinated compounds.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition and as a probe in molecular biology.

Basic Information

Product Name	6-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Pyrimidinone
CAS No.	83217-39-4
Molecular Formula	C11H7F3N2O2
Molecular Weight	256.18 g/mol
Synonyms	2-(3-(Trifluoromethyl)phenyl)-6-hydroxy-4(3H)-pyrimidinone; 6-Hydroxy-2-(3-trifluoromethylphenyl)-4(3H)-pyrimidinone; 4(3H)-Pyrimidinone, 6-hydroxy-2-[3-(trifluoromethyl)phenyl]-; 2-(alpha,alpha,α-Trifluoro-m-tolyl)-4,6-dihydroxypyrimidine; 6-Hydroxy-2-(3-trifluoromethylphenyl)-4-pyrimidinol; 83217-39-4
EINECS	Contact for details

Quality Control

Our production of 6-Hydroxy-2-[3-(Trifluoromethyl)Phenyl]-4(3H)-Pyrimidinone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.