Description

2-(4-Bromophenyl)-4,6-Dichloropyrimidine is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution for introducing complex substituents.
• Academic & R&D: Employed in universities and contract research organizations (CROs) for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-(4-Bromophenyl)-4,6-Dichloropyrimidine
CAS No.	83217-26-9
Molecular Formula	C10H5BrCl2N2
Molecular Weight	308.97 g/mol
Synonyms	4,6-Dichloro-2-(4-bromophenyl)pyrimidine; 2-(4-Bromophenyl)-4,6-dichloropyrimidine; 4'-Bromo-4,6-dichloro-2-phenylpyrimidine; 4,6-Dichloro-2-(p-bromophenyl)pyrimidine; 2-(p-Bromophenyl)-4,6-dichloropyrimidine; Pyrimidine, 2-(4-bromophenyl)-4,6-dichloro-; (4-Bromophenyl)-4,6-dichloropyrimidine
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)-4,6-Dichloropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.