Description

Epidermal Growth Factor (1-45) is a bioactive peptide fragment derived from the native human Epidermal Growth Factor protein. This compound is critical for research and development in regenerative medicine and advanced cell culture, as it specifically binds to and activates the EGF receptor, stimulating cellular proliferation and differentiation. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on wound healing, dermatology, and tissue engineering applications.

Application

• Biopharmaceutical R&D: Used as a key active ingredient in the development of novel wound healing and skin regeneration therapies.
• Advanced Cell Culture: Essential growth factor supplement for serum-free and defined media to promote the proliferation of epithelial and keratinocyte cell lines.
• Cosmeceutical Research: Investigated for its potential in high-end anti-aging and skin repair formulations.
• Tissue Engineering: Incorporated into scaffolds and biomaterials to enhance cell growth and tissue integration.
• Biochemical Research: Serves as a standard and reagent in signal transduction studies related to the EGFR pathway.
• Diagnostic Development: Potential use in assay development for detecting EGFR activity or related biomarkers.

Basic Information

Product Name	Epidermal Growth Factor (1-45)
CAS No.	83202-72-6
Molecular Formula	C212H337N61O66S7
Molecular Weight	Approx. 5070.8 g/mol
Synonyms	EGF (1-45); Human Epidermal Growth Factor Fragment 1-45; EGF Peptide (1-45); hEGF (1-45); Epidermal Growth Factor Human (1-45); EGF 1-45; CAS 83202-72-6; Recombinant Human EGF Fragment
EINECS	Contact for details

Quality Control

Our Epidermal Growth Factor (1-45) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing to ensure it meets high standards for research and development use. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity (Cell Proliferation Assay)	Conforms
Endotoxin	< 1.0 EU/µg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.