Description

(-)-1,2,3,6-Tetrahydro-n-(1-(Chloromethyl)Propyl)-1,3-Dimethyl-2,6-Dio Xo-7H-Purine-7-Acetamide is a specialized purine derivative with a complex molecular structure, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key chiral intermediate in the development of high-value pharmaceutical actives and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel therapeutic agents and other biologically active molecules. Our supply ensures high purity and batch-to-batch consistency for demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the synthesis of advanced pesticides and herbicides, leveraging its purine backbone for biological activity.
• Biochemical Research: Employed in academic and industrial laboratories as a standard or reagent for studying enzyme inhibition, receptor binding, and other purine-related biochemical pathways.
• Fine Chemical Production: Serves as a sophisticated building block for the custom synthesis of complex organic molecules for various high-tech applications.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.

Basic Information

Product Name	(-)-1,2,3,6-Tetrahydro-n-(1-(Chloromethyl)Propyl)-1,3-Dimethyl-2,6-Dio Xo-7H-Purine-7-Acetamide
CAS No.	83200-93-5
Molecular Formula	C15H20ClN5O3
Molecular Weight	353.80 g/mol
Synonyms	1,2,3,6-Tetrahydro-1,3-dimethyl-N-[1-(chloromethyl)propyl]-2,6-dioxo-7H-purine-7-acetamide; (1R,2S)-rel-1,2,3,6-Tetrahydro-1,3-dimethyl-N-[1-(chloromethyl)propyl]-2,6-dioxo-7H-purine-7-acetamide; 7H-Purine-7-acetamide, 1,2,3,6-tetrahydro-N-[1-(chloromethyl)propyl]-1,3-dimethyl-2,6-dioxo-; A derivative of 8-chlorotheophylline; Purine acetamide derivative
EINECS	Contact for details

Quality Control

Our (-)-1,2,3,6-Tetrahydro-n-(1-(Chloromethyl)Propyl)-1,3-Dimethyl-2,6-Dio Xo-7H-Purine-7-Acetamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identification by spectroscopic methods to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.