Description

Benzenamine, 4-(Difluoromethoxy)-3-Methyl- is a specialized aromatic amine derivative characterized by its difluoromethoxy and methyl substituents. This compound is a valuable high-purity intermediate for synthesizing advanced molecules in the pharmaceutical and agrochemical sectors. It is primarily required by R&D chemists and process development scientists working on novel active ingredients, where its unique structure enables the introduction of specific functional groups to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: Employed as a versatile reagent for introducing aniline derivatives with specific substitution patterns in medicinal and synthetic chemistry programs.

Basic Information

Product Name	Benzenamine, 4-(Difluoromethoxy)-3-Methyl-
CAS No.	83190-02-7
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	3-Methyl-4-(difluoromethoxy)aniline; 4-(Difluoromethoxy)-3-methylaniline; 4-Amino-2-methyl-1-(difluoromethoxy)benzene; 3-Methyl-4-(difluoromethoxy)benzenamine; 1-Amino-3-methyl-4-(difluoromethoxy)benzene; 2-Methyl-4-(difluoromethoxy)phenylamine
EINECS	Contact for details

Quality Control

Our Benzenamine, 4-(Difluoromethoxy)-3-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in containers stored within light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.