Description

2-Amino-6-Trifluoromethylbenzonorbornene is a specialized, high-purity organic intermediate featuring a unique norbornene scaffold functionalized with an amino group and a trifluoromethyl substituent. This compound matters for its role as a critical building block in advanced pharmaceutical and agrochemical synthesis, where its rigid, three-dimensional structure and fluorine content are leveraged to modulate biological activity and physicochemical properties. It is primarily needed by research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Key pharmaceutical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Building block in agrochemical research for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Precursor for ligand synthesis in catalysis, used to create novel chiral ligands for asymmetric synthesis.
• Monomer or functional additive in the development of specialty polymers and advanced materials with tailored thermal or optical properties.
• Starting material for fluorine chemistry research, exploring the unique effects of the trifluoromethyl group in molecular design.
• Reference standard and analytical reagent for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Amino-6-Trifluoromethylbenzonorbornene
CAS No.	83118-50-7
Molecular Formula	C₁₄H₁₄F₃N
Molecular Weight	253.26 g/mol
Synonyms	6-(Trifluoromethyl)-2-benzonorbornen-2-amine; 2-Amino-6-(trifluoromethyl)benzonorbornadiene; 2-Bicyclo[2.2.1]hept-5-ene-2-carbonitrile, 5-(trifluoromethyl)- (related); 5-(Trifluoromethyl)-2-bicyclo[2.2.1]hept-5-ene-2-carbonitrile; 2-Amino-6-trifluoromethyl-2,3-dihydro-1H-indene (tautomeric form); 83118-50-7; 2-Amino-6-(trifluoromethyl)norbornadiene benzene; 6-Trifluoromethyl-2-aminobenzonorbornene
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Trifluoromethylbenzonorbornene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.