Description

Fmoc-L-Val-Ome CAS NO 82911-80-6 is a protected amino acid derivative, specifically the Fmoc (9-fluorenylmethoxycarbonyl) derivative of L-valine methyl ester. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity intermediates for the development of therapeutic peptides, peptide hormones, and research biochemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key monomer for the automated, stepwise synthesis of custom peptides.
• Pharmaceutical Intermediates: In the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Biochemical Research: For studying protein structure-function relationships, enzyme substrates, and inhibitors.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.
• Antibody-Drug Conjugate (ADC) Development: As a component in the synthesis of linker-payload constructs.
• Proteomics and Molecular Biology: For the synthesis of labeled peptides used as standards or probes.

Basic Information

Product Name	Fmoc-L-Val-Ome
CAS No.	82911-80-6
Molecular Formula	C21H23NO4
Molecular Weight	353.41 g/mol
Synonyms	Fmoc-L-valine methyl ester; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanoic acid methyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine methyl ester; Fmoc-Val-OMe; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valinate; Fmoc-L-Val-OMe; Fmoc-Val-OMe
EINECS	Contact for details

Quality Control

Our Fmoc-L-Val-Ome is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for peptide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.