Description

Cyclo(Tyr-Leu) CAS NO 82863-65-8 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), composed of the amino acids L-Tyrosine and L-Leucine. This compound is of significant interest in pharmaceutical research and development due to its potential as a bioactive scaffold and its role in peptide stability and drug delivery systems. It serves as a critical intermediate and reference standard for researchers in medicinal chemistry, biochemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Used as a key building block in the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Acts as a core scaffold for studying structure-activity relationships (SAR) and developing new pharmacophores.
• Biochemical Research: Employed as a reference standard in analytical methods such as HPLC and mass spectrometry for peptide analysis.
• Drug Delivery Systems: Investigated for its potential in enhancing the stability, bioavailability, and targeted delivery of therapeutic peptides.
• Enzyme Inhibition Studies: Utilized in research to probe enzyme active sites and develop protease inhibitors.
• Cosmeceutical Applications: Explored for potential use in advanced skincare formulations due to its peptide nature.

Basic Information

Product Name	Cyclo(Tyr-Leu)
CAS No.	82863-65-8
Molecular Formula	C15H20N2O3
Molecular Weight	276.33 g/mol
Synonyms	Cyclo(L-Tyrosyl-L-Leucyl); Cyclo(L-Tyr-L-Leu); 3-Benzyl-6-isobutyl-2,5-piperazinedione; L-Tyrosyl-L-leucine anhydride; DKPs (Tyr-Leu); 2,5-Diketopiperazine, 3-benzyl-6-(2-methylpropyl)-; (3S,6S)-3-Benzyl-6-isobutylpiperazine-2,5-dione; L-Leucine, cyclic dipeptide with L-tyrosine
EINECS	Contact for details

Quality Control

Our Cyclo(Tyr-Leu) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and chiral purity analysis to ensure the correct stereochemistry. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.