Description

Poly-L-Threonine is a high-purity, enantiomerically pure form of the essential amino acid threonine, specifically the L-isomer. This compound is a critical building block in advanced biochemical research and pharmaceutical development due to its role in protein synthesis and metabolic pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require a consistent, high-quality chiral reagent for peptide synthesis, cell culture media, and metabolic studies.

Application

• Pharmaceutical Intermediates: A key chiral building block for the synthesis of therapeutic peptides, APIs (Active Pharmaceutical Ingredients), and complex drug molecules.
• Biochemical Research: Used as a standard and reagent in enzymatic studies, metabolic pathway analysis, and protein structure-function research.
• Cell Culture Media: An essential nutrient component in defined media for mammalian and microbial cell culture, supporting growth and protein expression.
• Nutraceutical Formulation: Incorporated into specialized amino acid supplements and clinical nutrition products requiring high-purity, bioavailable L-form amino acids.
• Cosmetic & Personal Care: Used in the formulation of high-end skin care products for its potential role in maintaining skin hydration and protein structure.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in laboratories.

Basic Information

Product Name	Poly-L-Threonine
CAS No.	82822-12-6
Molecular Formula	(C4H9NO3)n
Molecular Weight	n * 119.12 g/mol
Synonyms	L-Threonine Homopolymer; Poly(threonine); PThr; Poly(L-threonine); Poly(Thr); (2S,3R)-2-Amino-3-hydroxybutanoic acid homopolymer; H-Thr-OH homopolymer; NSC 334315
EINECS	Contact for details

Quality Control

Our Poly-L-Threonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Optical Rotation [α]	-28.0° to -32.0° (c=1 in H2O)
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.