Description

Lhrh, n-Ac-Pro(1)-(4-Cl-Phe)(2)-(2-Naphthyl-Ala)(3,6)- CAS NO 82778-57-2 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), featuring specific amino acid modifications at positions 1, 2, 3, and 6. This engineered structure is critical for enhancing biological stability and receptor binding affinity, making it a valuable tool for advanced research and development. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel LHRH-based therapeutics.
• Endocrinology Studies: Used in vitro and in vivo to study the hypothalamic-pituitary-gonadal axis, hormone regulation, and receptor interaction mechanisms.
• Oncology Research: Investigated for applications in hormone-dependent cancers, such as prostate and breast cancer, due to its potential to modulate hormone-sensitive pathways.
• Reproductive Biology: Employed in research concerning fertility, contraception, and disorders of the reproductive system.
• Biochemical Assay Development: Acts as a critical component in the development and validation of immunoassays, receptor binding assays, and other diagnostic tests.
• Peptide Chemistry & Conjugation: Used as a starting material or intermediate for further chemical modification, labeling, or conjugation in probe development.

Basic Information

Product Name	Lhrh, n-Ac-Pro(1)-(4-Cl-Phe)(2)-(2-Naphthyl-Ala)(3,6)- CAS NO 82778-57-2
CAS No.	82778-57-2
Molecular Formula	C64H83ClN14O13
Molecular Weight	1267.9 g/mol
Synonyms	Ac-Pro(1)-4-chloro-Phe(2)-D-2-Nal(6)-LHRH; LHRH Antagonist Analog; Modified Luteinizing Hormone-Releasing Hormone Peptide; [Ac-Pro1, 4-Cl-D-Phe2, D-2-Nal3,6]-LHRH; GnRH Antagonist Derivative; Gonadorelin Analog; LHRH (1-9) Nonapeptide Amide Derivative; Research Peptide 82778-57-2
EINECS	Contact for details

Quality Control

Every batch of our Lhrh peptide analog is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the rigorous standards required for research and development applications. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.