Description

4-(3-Fluorophenoxy)Phenol is a high-purity fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorophenoxy group and a phenolic hydroxyl, makes it an essential intermediate for creating high-performance materials and active pharmaceutical ingredients. This product is primarily targeted at research and development laboratories, pharmaceutical manufacturers, and specialty chemical producers engaged in creating novel polymers, agrochemicals, and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Liquid Crystal Materials: Used in the production of fluorinated monomers for high-stability liquid crystal displays (LCDs).
• Polymer Modification: Acts as a functional monomer or chain modifier to introduce fluorine and phenolic groups into engineering plastics, enhancing thermal and chemical resistance.
• Agrochemical Synthesis: Intermediate for developing new-generation herbicides and pesticides with improved efficacy and environmental profile.
• Dye and Pigment Industry: Building block for synthesizing specialized fluorinated dyes with unique color fastness and solubility properties.
• Research & Development: Serves as a versatile scaffold in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-(3-Fluorophenoxy)Phenol
CAS No.	82720-78-3
Molecular Formula	C12H9FO2
Molecular Weight	204.20 g/mol
Synonyms	4-(3-Fluorophenoxy)phenol; 1-Fluoro-3-(4-hydroxyphenoxy)benzene; 3-Fluorophenyl 4-hydroxyphenyl ether; 4-Hydroxy-3'-fluorodiphenyl ether; Phenol, 4-(3-fluorophenoxy)-; [1,1'-Biphenyl]-4-ol, 3'-fluoro-3-ether; FPP (abbreviation); 82720-78-3
EINECS	Contact for details

Quality Control

Every batch of 4-(3-Fluorophenoxy)Phenol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets a typical purity specification of ≥98.0% (by HPLC), with comprehensive control of related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. The compound is light-sensitive (store away from light) as indicated in its chemical properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5 %
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.