Description

Gastrin Heptadecapeptide, Nle(15)- is a synthetic, biologically active peptide analog of the gastrointestinal hormone gastrin. This compound is of significant value for research and development in the fields of endocrinology and gastroenterology, serving as a critical tool for studying gastric acid secretion and related physiological pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic and digestive system disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the mechanisms of gastrin receptor (CCK2R) activation and signaling.
• Pharmacological Assays: Essential for in vitro and in vivo bioassays to evaluate gastric acid secretion and the efficacy of potential acid-suppressant drugs.
• Drug Discovery: Serves as a key biochemical tool in high-throughput screening (HTS) campaigns to identify novel gastrin receptor agonists or antagonists.
• Diagnostic Development: Can be utilized in the development of immunoassays and other diagnostic tests for measuring gastrin levels or related biomarkers.
• Academic Studies: Employed in university and institutional research to explore the role of gastrin in cell proliferation, digestion, and potential links to certain pathologies.

Basic Information

Product Name	Gastrin Heptadecapeptide, Nle(15)-
CAS No.	82695-69-0
Molecular Formula	C97H124N18O31S2
Molecular Weight	2094.3 g/mol
Synonyms	Nle15-Gastrin I (2-17); Norleucine15-Gastrin I (2-17); Gastrin I (2-17), Nle15-; [Nle15]-Gastrin (2-17); Human Gastrin I (2-17), Nle15 analog; pGlu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 (Met15→Nle); CCK-2 Receptor Ligand
EINECS	Contact for details

Quality Control

Our Gastrin Heptadecapeptide, Nle(15)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with high-purity research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.