Description

Somatostatin, Iodo-Tyr(1)- is a chemically modified peptide analog of the endogenous hormone somatostatin. This iodinated derivative is a critical tool compound in biomedical research, particularly for receptor binding studies and the development of radiolabeled diagnostic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, oncology, and neurobiology.

Application

• Biochemical Research: Used as a high-affinity ligand for studying somatostatin receptor (SSTR) subtypes, their distribution, and signaling pathways.
• Radiopharmaceutical Development: Serves as a precursor for the synthesis of iodine-123 or iodine-131 labeled tracers for SPECT imaging of tumors expressing somatostatin receptors.
• In Vitro Diagnostics: Employed in the development and calibration of competitive immunoassays and receptor binding assays to quantify somatostatin or its analogs.
• Drug Discovery: Acts as a reference standard and a key intermediate in the design and screening of novel peptide-based therapeutics targeting SSTRs.
• Metabolic Studies: Utilized in experimental models to investigate the inhibitory effects of somatostatin on hormone secretion (e.g., growth hormone, insulin, glucagon).

Basic Information

Product Name	Somatostatin, Iodo-Tyr(1)-
CAS No.	82599-24-4
Molecular Formula	C76H104N18O19S2I
Molecular Weight	~1638.8 g/mol
Synonyms	Iodo-Tyr1-Somatostatin-14; [Tyr(I125)]Somatostatin-14 (precursor); Iodotyrosyl1-Somatostatin; Somatostatin-14, 1-(3-iodo-L-tyrosine); SRIF-14, Iodo-Tyr(1)-; Alamantide, iodinated; Growth hormone release-inhibiting factor, iodinated; H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: 3-14), 1-Iodo-Tyr
EINECS	Contact for details

Quality Control

Our Somatostatin, Iodo-Tyr(1)- is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.