Description

Cyclo(-Phe-Trp) is a cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids L-phenylalanine and L-tryptophan. This compound is of significant interest in pharmaceutical research and development due to its role as a key structural motif and potential biological activity. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, peptide synthesis, and biochemistry. The product is supplied under the identifier CAS 82597-82-8, ensuring precise identification for global sourcing and regulatory documentation.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Used as a reference standard or scaffold in drug discovery programs targeting various receptors and enzymes.
• Biochemical Tool: Employed in studies of peptide conformation, stability, and structure-activity relationships (SAR).
• Reference Standard: Provides a high-purity benchmark for analytical methods such as HPLC and LC-MS in quality control laboratories.
• Peptide Library Synthesis: Utilized in the generation of combinatorial libraries for high-throughput screening.
• Academic Research: Applied in university and institutional labs for fundamental studies in organic chemistry and peptide science.

Basic Information

Product Name	Cyclo(-Phe-Trp)
CAS No.	82597-82-8
Molecular Formula	C20H19N3O2
Molecular Weight	333.39 g/mol
Synonyms	Cyclo(L-phenylalanyl-L-tryptophyl); Cyclo(Phe-Trp); 3-Benzyl-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione; L-Phenylalanyl-L-tryptophan anhydride; DKPs; Diketopiperazine; Phe-Trp DKP; Cyclo(Phe-Trp) DKP
EINECS	Contact for details

Quality Control

Our Cyclo(-Phe-Trp) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.