Description

Deoxyhypusine is a key intermediate in the post-translational modification pathway of the eukaryotic translation initiation factor 5A (eIF5A). This compound matters significantly for its role in the biosynthesis of hypusine, a unique amino acid critical for cellular proliferation and protein synthesis. It is primarily needed by researchers and manufacturers in the fields of biochemical research, pharmaceutical development, and life science studies.

Application

• Biochemical Research: Used as a critical precursor in studies of the hypusination pathway and eIF5A function.
• Pharmaceutical Development: Serves as a reference standard or intermediate in the development of therapeutics targeting cellular growth and proliferation.
• Enzymology Studies: Employed as a substrate for deoxyhypusine synthase (DHPS) in enzyme activity and inhibition assays.
• Cell Biology: Utilized in research investigating the role of eIF5A in apoptosis, aging, and cellular stress response.
• Academic Research: A vital tool for universities and research institutions studying molecular biology and post-translational modifications.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized diagnostic kits and reagents.

Basic Information

Product Name	Deoxyhypusine
CAS No.	82543-85-9
Molecular Formula	C14H30N4O3
Molecular Weight	302.41 g/mol
Synonyms	N1-(4-Aminobutyl)-N2-(3-aminopropyl)-L-lysine; (2S)-2-Amino-6-[[(4-aminobutyl)amino]amino]hexanoic acid; N6-(4-Aminobutyl)-N2-(3-aminopropyl)-L-lysine; Deoxyhypusine free base; DHP; eIF5A precursor intermediate
EINECS	Contact for details

Quality Control

Our Deoxyhypusine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification, to ensure it meets high-purity research standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.