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Glycyl-Glycyl-Tyrosine n-Methylamide CAS NO 82486-67-7


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CAS No.:82486-67-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Glycyl-Glycyl-Tyrosine n-Methylamide is a synthetic tripeptide derivative featuring a C-terminal methylamide modification. This structural feature enhances its metabolic stability and makes it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications ranging from biochemical studies to the synthesis of more complex peptide-based therapeutics. The compound is supplied to meet the stringent purity and consistency requirements of these high-value industries.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide drugs and active pharmaceutical ingredients (APIs).
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease specificity and function.
  • Peptide Library Synthesis: Employed in combinatorial chemistry for the creation of diverse peptide libraries used in drug discovery screening.
  • Neuroscience Research: Acts as a model compound for studying peptide transport, stability, and receptor interactions within biological systems.
  • Reference Standard: Provides a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name Glycyl-Glycyl-Tyrosine n-Methylamide
CAS No. 82486-67-7
Molecular Formula C₁₇H₂₄N₄O₅
Molecular Weight 364.40 g/mol
Synonyms Gly-Gly-Tyr-NHMe; H-Gly-Gly-Tyr-NHCH₃; N-Methyl-Glycyl-Glycyl-Tyrosinamide; Glycylglycyl-L-tyrosine N-methylamide; L-Tyrosine, glycylglycyl-, N-methylamide; GGTYR-NHME; Peptide GG-Y-NHMe
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Quality Control

Our Glycyl-Glycyl-Tyrosine n-Methylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference
Assay (HPLC) ≥ 98.0%
Purity (HPLC) ≥ 98.5%
Optical Rotation -20° to -25° (c=1 in H₂O)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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