Description

11-(3-Dimethylaminopropyl)-11H-Dibenz(B,F)-1,4-Oxathiepin Hydrogen Oxa Late Hemihydrate is a high-purity, complex organic compound primarily utilized as a key intermediate in advanced pharmaceutical synthesis. Its value lies in enabling the development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology research sectors. This compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on creating new molecular entities. We supply this material with stringent quality control to ensure batch-to-batch consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis for constructing complex dibenzoxathiepin ring systems.
• Preclinical Studies: Utilized in the preparation of compounds for pharmacological screening and biological evaluation.

Basic Information

Product Name	11-(3-Dimethylaminopropyl)-11H-Dibenz(B,F)-1,4-Oxathiepin Hydrogen Oxa Late Hemihydrate
CAS No.	82387-05-1
Molecular Formula	C19H22N2O3S • 0.5H2O
Molecular Weight	355.46 g/mol (anhydrous basis)
Synonyms	11-(3-Dimethylaminopropyl)dibenz[b,f][1,4]oxathiepin hydrogen oxalate hemihydrate; Zotepine Oxalate Hemihydrate; Zotepine Hydrogen Oxalate Hemihydrate; Lodopin; Nipolept; Oxalate salt of Zotepine; 2-[(8-Chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine oxalate hemihydrate
EINECS	Contact for details

Quality Control

Our 11-(3-Dimethylaminopropyl)-11H-Dibenz(B,F)-1,4-Oxathiepin Hydrogen Oxa Late Hemihydrate is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and conformity to established specifications. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, ensuring it meets the rigorous standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	2.0% - 3.5% (theoretical for hemihydrate: ~2.5%)
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.