Description

Boc-Met-Enkephalin-T-Butyl Ester is a protected peptide derivative, specifically a key intermediate in the synthesis of Met-enkephalin, an endogenous opioid peptide. This compound is essential for researchers and manufacturers requiring precise control over peptide assembly and side-chain protection strategies. It is primarily utilized in pharmaceutical R&D, biochemical studies, and the production of reference standards for neurological research.

Application

• Pharmaceutical Intermediate: Critical building block in the solid-phase or solution-phase synthesis of Met-enkephalin and related opioid peptide analogs.
• Biochemical Research: Used in studies investigating opioid receptor binding, signal transduction pathways, and the structure-activity relationships (SAR) of neuropeptides.
• Reference Standard: Serves as a high-purity chromatographic standard for quality control in peptide manufacturing and analytical method development.
• Neuroscience Probes: A precursor for developing labeled (e.g., fluorescent, radioactive) peptides used in imaging and diagnostic applications.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in neurochemistry and peptide science.

Basic Information

Product Name	Boc-Met-Enkephalin-T-Butyl Ester
CAS No.	82362-16-1
Molecular Formula	C33H53N5O8S
Molecular Weight	679.87 g/mol
Synonyms	Boc-Tyr-Gly-Gly-Phe-Met-OtBu; Boc-Met-Enkephalin tert-Butyl Ester; N-tert-Butoxycarbonyl-Methionine Enkephalin T-Butyl Ester; Boc-[Met5]-Enkephalin T-Butyl Ester; H-Tyr-Gly-Gly-Phe-Met-OH (Boc, OtBu protected); Boc-Enkephalin (Met) T-Butyl Ester; Opioid Peptide Intermediate 82362-16-1
EINECS	Contact for details

Quality Control

Our Boc-Met-Enkephalin-T-Butyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not intended for direct human use as an API, production adheres to principles of current Good Manufacturing Practice (cGMP) where applicable for intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.