Description

7β,8-Epoxy-11α,14-Dihydroxy-12-Oxo-3β,2α-[[(2S,3S,4R,6R)-Tetrahydro-3-Hydroxy-4-Methoxy-6-Methyl-2H-Pyran-2,3-Diyl]Bis(Oxy)]Carda-4,20(22)-Dienolide is a complex cardenolide glycoside derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel cardiac glycosides and other specialized therapeutic agents. It serves as a key building block for medicinal chemists and advanced manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated synthetic precursor in the research and development of new cardiac drugs and other bioactive molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop novel therapeutic agents with improved efficacy and safety profiles.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Research: Employed in pharmacological studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition and other biological pathways.
• Process Development: Utilized in scaling up synthetic routes for the production of complex natural product derivatives and analogs.

Basic Information

Item	Details
Product Name	7β,8-Epoxy-11α,14-Dihydroxy-12-Oxo-3β,2α-[[(2S,3S,4R,6R)-Tetrahydro-3-Hydroxy-4-Methoxy-6-Methyl-2H-Pyran-2,3-Diyl]Bis(Oxy)]Carda-4,20(22)-Dienolide
CAS No.	82345-35-5
Molecular Formula	C30H40O11
Molecular Weight	576.64 g/mol
Synonyms	3β,2α-[[(2S,3S,4R,6R)-Tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]-7β,8-epoxy-11α,14-dihydroxy-12-oxo-carda-4,20(22)-dienolide; 7β,8-Epoxy-11α,14-dihydroxy-12-oxo-3β,2α-[[(2S,3S,4R,6R)-tetrahydro-3-hydroxy-4-methoxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]carda-4,20(22)-dienolide; Cardenolide glycoside derivative; 3β,2α-Bis-O-(tetrahydro-3-hydroxy-4-methoxy-6-methylpyranosyl)oxy-7β,8-epoxy-11α,14-dihydroxy-12-oxo-carda-4,20(22)-dienolide
EINECS	Contact for details

Quality Control

Our 7β,8-Epoxy-11α,14-Dihydroxy-12-Oxo-3β,2α-[[(2S,3S,4R,6R)-Tetrahydro-3-Hydroxy-4-Methoxy-6-Methyl-2H-Pyran-2,3-Diyl]Bis(Oxy)]Carda-4,20(22)-Dienolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.