Description

Boc-D-Ser(Bzl)-Osu is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemistry and side-chain protection to ensure the fidelity of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled, sequential addition of D-serine benzyl ether into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex, biologically active peptides and peptidomimetics in solution.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the research and development of peptide-based drugs, including hormones and enzyme inhibitors.
• Bioconjugation: Employed to introduce protected serine residues into proteins or other biomolecules for further chemical modification.
• Combinatorial Chemistry: Utilized in libraries for drug discovery to create diverse arrays of peptide analogs.
• Academic & Industrial Research: A fundamental tool for studying peptide structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	Boc-D-Ser(Bzl)-Osu
CAS No.	82155-85-9
Molecular Formula	C19H24N2O7
Molecular Weight	392.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-O-benzyl-D-serine N-Hydroxysuccinimide Ester; Boc-D-Serine(Bzl)-OSu; Boc-O-Benzyl-D-serine N-succinimidyl ester; (2R)-3-(Benzyloxy)-2-[[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoic acid 2,5-dioxopyrrolidin-1-yl ester; tert-Butyl (R)-(1-(benzyloxy)-3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropan-2-yl)carbamate; Boc-D-Ser(Bzl)-ONSu; D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, 2,5-dioxo-1-pyrrolidinyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Ser(Bzl)-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, NMR for structural confirmation, and loss on drying. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Loss on Drying	≤0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.