Description

2-(2-Fluorophenoxy)Benzaldehyde is a specialized aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a benzaldehyde core linked via an ether bridge to a fluorinated phenyl ring, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the fluorine atom.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorophenoxy moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for Schiff base ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material fabrication.
• Organic Electronic Materials: Investigated as a building block for π-conjugated systems in the development of organic light-emitting diodes (OLEDs) and semiconductors.
• Fluorescent Probe Synthesis: Utilized in the creation of fluorophore derivatives for biochemical sensing and imaging applications.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring specific fluorinated aromatic aldehydes.

Basic Information

Product Name	2-(2-Fluorophenoxy)Benzaldehyde
CAS No.	82097-82-3
Molecular Formula	C₁₃H₉FO₂
Molecular Weight	216.21 g/mol
Synonyms	2-(2-Fluorophenoxy)benzaldehyde; Benzaldehyde, 2-(2-fluorophenoxy)-; o-(2-Fluorophenoxy)benzaldehyde; 2-Fluorophenyl 2-formylphenyl ether; 2'-Formyl-2-fluorodiphenyl ether; 2-(2-Fluorophenoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.