Description

(2S,4S)-4-Benzyl-Pyrrolidine-2-Carboxylic Acid CAS NO 82087-73-8 is a high-purity, non-proteinogenic amino acid derivative featuring a constrained pyrrolidine ring with defined stereochemistry. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise three-dimensional control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, peptide mimetics, and the development of novel bioactive compounds.

Application

• Pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Chiral building block in asymmetric synthesis and medicinal chemistry research.
• Precursor for the development of peptidomimetics and constrained peptide analogs.
• Key starting material for organocatalysts and chiral ligands used in stereoselective transformations.
• Intermediate in the research and production of specialty chemicals and advanced materials.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(2S,4S)-4-Benzyl-Pyrrolidine-2-Carboxylic Acid
CAS No.	82087-73-8
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	(2S,4S)-4-Benzyl-2-pyrrolidinecarboxylic acid; (2S,4S)-4-Benzylproline; (4S)-4-Benzyl-L-proline; 4-Benzyl-L-proline; (2S,4S)-4-Benzylpyrrolidine-2-carboxylic acid; 4-Benzyl-(2S,4S)-pyrrolidine-2-carboxylic acid; L-4-Benzylproline; (S,S)-4-Benzylproline
EINECS	Contact for details

Quality Control

Our (2S,4S)-4-Benzyl-Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of moisture from the air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.