Description

Melitin CAS NO 81944-31-2 is a synthetic peptide compound of significant interest in biochemical research and development. This product is valued for its role as a key reference standard and active ingredient in the study of membrane interactions and cytolytic activity. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in antimicrobial, anticancer, and biophysical research. Our supply ensures high purity and batch-to-batch consistency critical for reliable experimental results.

Application

• Biomedical Research: Used as a model peptide for studying the mechanisms of cell lysis, pore formation in lipid membranes, and antimicrobial activity.
• Pharmaceutical Development: Serves as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel therapeutic agents, particularly in oncology and infectious disease.
• Biophysical Studies: Employed in investigations of peptide-lipid interactions, membrane dynamics, and the structural basis of peptide toxicity.
• Antimicrobial Agent Research: Acts as a benchmark compound in the development and screening of new antimicrobial peptides (AMPs) and biofilm-disrupting agents.
• Cell Biology: Utilized in controlled experiments to induce apoptosis or necrosis in cell cultures for mechanistic studies.
• Diagnostic Reagent Component: Incorporated into specialized assay kits and reagents designed for cytotoxicity testing and membrane permeability studies.

Basic Information

Product Name	Melitin
CAS No.	81944-31-2
Molecular Formula	C₁₃₁H₂₂₉N₃₉O₃₁
Molecular Weight	2846.5 g/mol
Synonyms	Melittin; Bee Venom Peptide; Apamin; Apidin; Melittin (Honey Bee); 26-L-Isoleucine-melittin; Honeybee Venom Melittin; Melittin I; Melittin II; Melittin (porcine); Melittin (synthetic)
EINECS	Contact for details

Quality Control

Our Melitin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, mass spectrometry for identity confirmation, and stringent controls for residual solvents and endotoxins. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.