Description

4-Methyl-6-Hydroxy-5-(2-Propynyl)-2-Pyrimidinamine is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables targeted molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its pyrimidine core for biological activity.
• Fine Chemical Production: Serves as a versatile precursor in the manufacture of complex specialty chemicals and performance materials.
• Biochemical Research: Employed in life science research as a molecular probe or scaffold for studying enzyme interactions and biological pathways.
• Material Science: Potential intermediate in the development of organic electronic materials or metal-organic frameworks (MOFs) due to its functional groups.

Basic Information

Product Name	4-Methyl-6-Hydroxy-5-(2-Propynyl)-2-Pyrimidinamine
CAS No.	81887-01-6
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	5-(Prop-2-yn-1-yl)-6-methylpyrimidine-2,4-diamine; 2-Amino-4-methyl-6-hydroxy-5-prop-2-ynylpyrimidine; 4-Methyl-6-hydroxy-5-prop-2-ynylpyrimidin-2-amine; 5-(2-Propynyl)-6-methyl-2,4-pyrimidinediamine; 6-Methyl-5-(prop-2-yn-1-yl)pyrimidine-2,4-diol (tautomer); CAS 81887-01-6
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-Hydroxy-5-(2-Propynyl)-2-Pyrimidinamine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request, providing full traceability and compliance support for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.