Description

5-Chloro-1-(2-Hydroxy-Ethoxymethyl)-1H-Pyrimidine-2,4-Dione is a high-purity pyrimidine derivative, a key building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its precise reactivity and structural utility.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer drug candidates.
• Nucleoside Analogue Synthesis: Used in the research and production of modified nucleosides for therapeutic applications.
• Agrochemical Research: Serves as a building block for developing new herbicides and plant growth regulators.
• Biochemical Research: Employed in academic and industrial labs for studying enzyme inhibitors and metabolic pathways.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	5-Chloro-1-(2-Hydroxy-Ethoxymethyl)-1H-Pyrimidine-2,4-Dione
CAS No.	81777-50-6
Molecular Formula	C7H9ClN2O4
Molecular Weight	220.61 g/mol
Synonyms	5-Chloro-1-(2-hydroxyethoxymethyl)uracil; 5-Chloro-1-(2-hydroxyethoxymethyl)-2,4(1H,3H)-pyrimidinedione; 5-Chloro-1-(2-hydroxyethoxy)methyluracil; 5-Chloro-1-Hydroxyethoxymethyluracil; 81777-50-6; 5-Chloro-HEC-Ura; 5-Cl-HEMU
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(2-Hydroxy-Ethoxymethyl)-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.