Description

Acetic Acid 2-(5-Chloro-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Ylmethoxy)-Ethyl Ester CAS NO 81777-43-7 is a specialized pyrimidine derivative ester, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in providing a functionalized scaffold for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development laboratories and production facilities in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer agents, particularly those based on modified nucleoside/nucleotide structures.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing prodrugs or as a precursor in multi-step synthetic routes for new chemical entities.
• Biochemical Research: Serves as a substrate or inhibitor analog in enzymatic studies, especially those involving pyrimidine metabolism.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Agrochemical Research: Potential intermediate in the development of new herbicides or plant growth regulators with pyrimidine cores.

Basic Information

Product Name	Acetic Acid 2-(5-Chloro-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Ylmethoxy)-Ethyl Ester
CAS No.	81777-43-7
Molecular Formula	C11H13ClN2O6
Molecular Weight	304.68 g/mol
Synonyms	1-[(2-Acetoxyethoxy)methyl]-5-chlorouracil; 5-Chloro-1-[(2-acetoxyethoxy)methyl]uracil; 5-Chloro-1-[[2-(acetyloxy)ethoxy]methyl]-2,4(1H,3H)-pyrimidinedione; 2-(5-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethoxy)ethyl acetate; 1-[(2-Acetyloxyethoxy)methyl]-5-chlorouracil; 5-Chloro-1-(2-acetoxyethoxymethyl)uracil; ACDE
EINECS	Contact for details

Quality Control

Our Acetic Acid 2-(5-Chloro-2,4-Dioxo-3,4-Dihydro-2H-Pyrimidin-1-Ylmethoxy)-Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.