Description

Phe-Leu Amide Hydrochloride is a high-purity dipeptide derivative, specifically the hydrochloride salt of the phenylalanine-leucine amide. This compound serves as a critical building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme studies, and metabolic pathway analysis.
• Peptide Synthesis: Serves as a protected dipeptide building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Phe-Leu Amide Hydrochloride
CAS No.	81638-86-0
Molecular Formula	C15H23N3O2 • HCl
Molecular Weight	313.82 g/mol (for free base: 277.36 g/mol)
Synonyms	L-Phenylalanyl-L-leucinamide hydrochloride; Phe-Leu-NH2 • HCl; N-(L-Phenylalanyl)-L-leucinamide hydrochloride; L-Phe-L-Leu-NH2 hydrochloride; F-L-NH2 • HCl; Phenylalanine-leucine amide hydrochloride; 2-[(2-Amino-1-oxo-3-phenylpropyl)amino]-4-methylpentanamide hydrochloride
EINECS	Contact for details

Quality Control

Our Phe-Leu Amide Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting purity, appearance, and specific tests are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.