Description

4(1H)-Pyrimidinone, 5-Acetyl-2-Amino- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize potential drug candidates, agrochemicals, and other biologically relevant compounds. Its unique pyrimidinone scaffold with acetyl and amino substituents offers versatile sites for further chemical modification.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage its heterocyclic core structure.
• Biochemical Probe Synthesis: Serves as a precursor for creating molecular probes and inhibitors used in biochemical and pharmacological research to study enzyme mechanisms.
• Material Science Precursor: Employed in the research and development of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry and medicinal chemistry.
• Custom Synthesis: A starting material for custom synthesis services, enabling the production of tailored derivatives for specific client projects.

Basic Information

Item	Details
Product Name	4(1H)-Pyrimidinone, 5-Acetyl-2-Amino- (9Ci)
CAS No.	81633-28-5
Molecular Formula	C6H7N3O2
Molecular Weight	153.14 g/mol
Synonyms	5-Acetyl-2-aminopyrimidin-4(1H)-one; 2-Amino-5-acetyl-4(1H)-pyrimidinone; 5-Acetyl-2-amino-4-pyrimidinol; 2-Amino-5-acetyl-4-pyrimidinol; 5-Acetyl-2-amino-4(1H)-pyrimidinone; 2-Amino-5-acetyl-4-hydroxypyrimidine; 4-Hydroxy-2-amino-5-acetylpyrimidine; 5-Acetyl-2-amino-4(3H)-pyrimidinone (tautomer)
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinone, 5-Acetyl-2-Amino- (9Ci) is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.