Description

n-Ac-(4-Cl-Phe)(1)-(4-Cl-Phe)(2)-Trp(3)-Lys(6)-Alanh2(10)-Lhrh CAS NO 81608-55-1 is a synthetic peptide analog of luteinizing hormone-releasing hormone (LHRH). This compound is engineered for high receptor affinity and metabolic stability, making it a critical tool in advanced endocrinology research and therapeutic development. It is primarily utilized by pharmaceutical R&D teams and biotechnology companies focused on developing novel treatments for hormone-dependent conditions.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel LHRH-based therapeutics.
• Endocrinology Studies: Used in vitro and in vivo to study the LHRH receptor signaling pathway, hormone regulation, and feedback mechanisms.
• Preclinical Drug Evaluation: Employed in animal models to assess the efficacy, pharmacokinetics, and safety profile of new hormonal therapies.
• Biochemical Assay Development: Acts as a high-purity ligand in the development and validation of competitive binding assays (e.g., ELISA, RIA) and receptor characterization studies.
• Peptide Chemistry & Conjugation: Provides a structurally complex scaffold for further chemical modification, conjugation, or prodrug development.

Basic Information

Product Name	n-Ac-(4-Cl-Phe)(1)-(4-Cl-Phe)(2)-Trp(3)-Lys(6)-Alanh2(10)-Lhrh
CAS No.	81608-55-1
Molecular Formula	C72H92Cl2N16O13
Molecular Weight	~1444.5 g/mol
Synonyms	Ac-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 (acetate); LHRH Antagonist (Analog); Gonadotropin-Releasing Hormone Antagonist; Cetrorelix Acetate Impurity/Intermediate; Acetylated LHRH Peptide; GnRH Antagonist Peptide; [Ac-D-2-Nal1, D-4-Cl-Phe2, D-3-Pal3, Arg5, D-Cit6, D-Ala10]-LHRH
EINECS	Contact for details

Quality Control

Our n-Ac-(4-Cl-Phe)(1)-(4-Cl-Phe)(2)-Trp(3)-Lys(6)-Alanh2(10)-Lhrh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	3.0% - 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.