Description

Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Trp(3)-Arg(6)-Alanh2(10)- CAS NO 81608-49-3 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), featuring specific amino acid substitutions to modulate its biological activity and stability. This compound is of significant interest for research and development in advanced therapeutic applications due to its targeted interaction with hormone receptors. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of novel hormone-based therapeutics.
• Endocrinology Studies: For investigating the structure-activity relationship (SAR) of LHRH analogs and their effects on the hypothalamic-pituitary-gonadal axis.
• Oncology Research: Exploration of potential applications in targeted cancer treatments, particularly for hormone-sensitive cancers like prostate and breast cancer.
• Reproductive Medicine: Used in preclinical studies for developing treatments for fertility disorders and related endocrine conditions.
• Biochemical Reagent: Serves as a high-purity reference standard or reagent in analytical laboratories for method development and validation.
• Peptide Chemistry: Valuable building block for further chemical modification and synthesis of more complex peptide conjugates in specialized organic synthesis.

Basic Information

Item	Detail
Product Name	Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Trp(3)-Arg(6)-Alanh2(10)- CAS NO 81608-49-3
CAS No.	81608-49-3
Molecular Formula	C64H83ClN18O12
Molecular Weight	1283.9 g/mol (approx.)
Synonyms	Acetyl-4-chloro-D-Phe1, D-Trp3, D-Arg6, D-Ala10-LHRH; [Ac-4-Cl-D-Phe1, D-Trp3, D-Arg6, D-Ala10]-LHRH; LHRH Antagonist Analog; Gonadotropin-Releasing Hormone (GnRH) Antagonist Analog; LHRH (4-10) fragment analog; Synthetic Luteinizing Hormone-Releasing Hormone Derivative; Peptide LHRH Antagonist; GnRH Analog 81608-49-3
EINECS	Contact for details

Quality Control

Our Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Trp(3)-Arg(6)-Alanh2(10)- CAS NO 81608-49-3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity analysis, to ensure it meets high-grade research specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.