Description

Lorzafone [Usan:Inn] CAS NO 81603-65-8 is a pharmaceutical compound recognized by the United States Adopted Name (USAN) and International Nonproprietary Name (INN) systems. This designation highlights its significance as a well-defined active pharmaceutical ingredient (API) for research and development. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in neuropharmacology and therapeutic agent discovery.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key intermediate or reference standard in the discovery and preclinical testing of new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the controlled synthesis and formulation studies for potential central nervous system (CNS) targeting drugs.
• Biochemical Research: Employed in studies investigating ligand-receptor interactions, particularly those related to benzodiazepine receptor sites.
• Reference Standard: Acts as a high-purity analytical standard for method development, validation, and quality control in analytical laboratories.
• Metabolite Studies: Utilized in pharmacological and toxicological research to understand metabolic pathways and identify potential metabolites.

Basic Information

Item	Detail
Product Name	Lorzafone [Usan:Inn]
CAS No.	81603-65-8
Molecular Formula	C17H14ClN3O2
Molecular Weight	327.76 g/mol
Synonyms	Lorzafone; 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; CM-7117; USAN/INN: Lorzafone; (2H)-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-
EINECS	Contact for details

Quality Control

Our Lorzafone is manufactured and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via techniques such as HPLC, IR, and NMR to ensure it meets high-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.