Description

2,5-Difluorophenylglyoxal Hydrate is a high-purity, fluorinated aromatic glyoxal derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which can significantly influence the electronic properties, metabolic stability, and binding affinity of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for creating novel herbicides and fungicides with enhanced activity and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Material Research: Intermediate for developing advanced polymers, liquid crystals, and electronic materials with unique properties.
• Heterocyclic Chemistry: Versatile starting material for constructing fluorinated quinoxalines, imidazoles, and other nitrogen-containing heterocycles.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for studying biological processes.

Basic Information

Product Name	2,5-Difluorophenylglyoxal Hydrate
CAS No.	81593-28-4
Molecular Formula	C8H6F2O3 • xH2O
Molecular Weight	188.13 (Anhydrous basis)
Synonyms	2,5-Difluorobenzoylformaldehyde Hydrate; (2,5-Difluorophenyl)-oxoacetaldehyde Hydrate; 2,5-Difluorophenylglyoxal Monohydrate; 2,5-Difluoro-α-oxobenzeneacetaldehyde Hydrate; Glyoxal, (2,5-difluorophenyl)-, hydrate; 2,5-Difluorophenyl-α-ketoaldehyde Hydrate
EINECS	Contact for details

Quality Control

Our 2,5-Difluorophenylglyoxal Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.