Description

1-(3-Fluorophenyl)-2,2,2-Trifluoroethanol is a high-value fluorinated aromatic building block, prized for its unique chemical structure that combines a fluorinated phenyl ring with a trifluoroethanol moiety. This compound is essential for introducing fluorine atoms and specific functional groups into target molecules, significantly altering their physical, chemical, and biological properties. It is primarily sought after by R&D chemists and process developers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorine to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorinated structure can improve activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display and lighting technologies.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to produce specialty polymers with enhanced chemical resistance, thermal stability, or unique surface properties.
• Organic Synthesis & Catalysis: Employed as a versatile reagent or ligand precursor in asymmetric synthesis and catalytic reactions.

Basic Information

Product Name	1-(3-Fluorophenyl)-2,2,2-Trifluoroethanol
CAS No.	81577-10-8
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	3-Fluoro-α-(trifluoromethyl)benzyl alcohol; 1-(3-Fluorophenyl)-2,2,2-trifluoroethan-1-ol; α-(Trifluoromethyl)-3-fluorobenzyl alcohol; m-Fluoro-α-(trifluoromethyl)benzyl alcohol; 3-Fluorobenzyl alcohol, α-(trifluoromethyl)-; (3-Fluorophenyl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom purity grades, including research and GMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.