Description

2-Chloro-4-Benzyloxy-5-Fluoropyrimidine is a high-value fluorinated pyrimidine derivative, a key building block in modern synthetic organic chemistry. Its molecular structure, featuring both chloro and benzyloxy substituents on a fluoropyrimidine core, makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of antiviral, anticancer, and other biologically active drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and stability.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Material Science: Potential intermediate for the synthesis of specialty chemicals, dyes, and functional materials requiring specific fluorinated heterocyclic structures.

Basic Information

Product Name	2-Chloro-4-Benzyloxy-5-Fluoropyrimidine
CAS No.	81560-11-4
Molecular Formula	C11H8ClFN2O
Molecular Weight	238.65 g/mol
Synonyms	5-Fluoro-2-chloro-4-(phenylmethoxy)pyrimidine; 4-(Benzyloxy)-2-chloro-5-fluoropyrimidine; 2-Chloro-4-(benzyloxy)-5-fluoropyrimidine; 2-Chloro-5-fluoro-4-(phenylmethoxy)pyrimidine; 81560-11-4; Pyrimidine, 2-chloro-4-(benzyloxy)-5-fluoro-; 4-Benzyloxy-2-chloro-5-fluoropyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Benzyloxy-5-Fluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.