Description

Lhrh, n-Ac-Ala(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 81557-54-2 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), specifically modified with an N-terminal acetyl group and halogenated phenylalanine residues. This compound is a critical research-grade biochemical tool used for studying hormone-receptor interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, oncology, and reproductive medicine.

Application

• Biochemical Research: As a high-purity reference standard for the study of gonadotropin-releasing hormone (GnRH) receptor binding and activation mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or lead compound in the discovery and development of novel therapeutic agents targeting hormone-dependent conditions.
• Endocrinology Studies: Used in in vitro and in vivo models to investigate the hypothalamic-pituitary-gonadal axis and related disorders.
• Oncology Research: Applied in preclinical studies for cancers influenced by hormonal pathways, such as prostate and breast cancer.
• Peptide Chemistry: Acts as a building block or model compound for studying peptide stability, modification, and structure-activity relationships (SAR).
• Diagnostic Reagent Manufacturing: Potential use in the formulation of calibration standards for diagnostic assays measuring LHRH or related hormones.

Basic Information

Product Name	Lhrh, n-Ac-Ala(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 81557-54-2
CAS No.	81557-54-2
Molecular Formula	C64H83ClN16O12
Molecular Weight	1287.9 g/mol
Synonyms	Ac-Ala(1)-4-Chloro-Phe(2)-Trp(3,6)-LHRH; Acetyl-Ala-Chloro-Phe-Trp-LHRH; LHRH Analog (Ac-Ala-1, 4-Cl-Phe-2, Trp-3,6); GnRH Analog; Luteinizing Hormone-Releasing Hormone Peptide Analog; Gonadorelin Analog; [Ac-Ala1, 4-Cl-D-Phe2, D-Trp3,6]-LHRH; Research Peptide 81557-54-2
EINECS	Contact for details

Quality Control

Our Lhrh, n-Ac-Ala(1)-(4-Cl-Phe)(2)-Trp(3,6)- CAS NO 81557-54-2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.