Description

2-(Chloromethyl)-7-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One is a high-value, heterocyclic organic compound that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique fused-ring structure containing thiadiazole and pyrimidine moeties makes it a versatile building block for the development of novel active ingredients. This compound is primarily sought after by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Building block for developing next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Serves as a versatile scaffold for creating complex heterocyclic libraries for high-throughput screening in drug discovery.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and medicinal chemistry at universities and CROs (Contract Research Organizations).

Basic Information

Product Name	2-(Chloromethyl)-7-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One
CAS No.	81516-46-3
Molecular Formula	C8H6ClN3OS
Molecular Weight	227.67 g/mol
Synonyms	2-(Chloromethyl)-7-methyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one; 7-Methyl-2-(chloromethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one; [1,3,4]Thiadiazolo[3,2-a]pyrimidin-5-one, 2-(chloromethyl)-7-methyl-; Thiadiazolopyrimidinone derivative; CAS 81516-46-3
EINECS	Contact for details

Quality Control

Our production of 2-(Chloromethyl)-7-Methyl-5H-[1,3,4]Thiadiazolo[3,2-A]Pyrimidin-5-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.