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Lhrh, Rhodamine-Lys(6)- CAS NO 81447-76-9
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CAS No.:81447-76-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Lhrh, Rhodamine-Lys(6)- CAS NO 81447-76-9 is a chemically modified peptide derivative, specifically a rhodamine-labeled analog of the luteinizing hormone-releasing hormone (LHRH). This compound matters for researchers and developers as it provides a powerful fluorescent probe for tracking, imaging, and studying the behavior and localization of LHRH and its receptors in biological systems. Professionals in pharmaceutical R&D, biochemical research, and diagnostic assay development need this high-purity reagent for advanced studies in endocrinology, oncology, and targeted drug delivery.
Application
- Biomedical Research & Imaging: Used as a fluorescent tracer in confocal microscopy and flow cytometry to visualize LHRH receptor expression and internalization in cell cultures and tissue samples.
- Drug Discovery & Development: Serves as a critical tool for screening and validating potential LHRH-targeting therapeutics, including antagonists and agonists for cancer treatment.
- Diagnostic Assay Development: Employed in the development of sensitive fluorescence-based immunoassays (FLISA) and receptor binding assays for clinical and research diagnostics.
- Targeted Delivery Studies: Acts as a model conjugate for researching ligand-directed delivery systems, helping to understand the pharmacokinetics of peptide-drug conjugates.
- Academic & Institutional Research: Fundamental research in neuroendocrinology, reproductive biology, and signal transduction pathways involving the LHRH receptor.
Basic Information
| Product Name | Lhrh, Rhodamine-Lys(6)- CAS NO 81447-76-9 |
| CAS No. | 81447-76-9 |
| Molecular Formula | C80H105N19O16 |
| Molecular Weight | 1564.8 g/mol |
| Synonyms | Rhodamine-LHRH; LHRH-Rhodamine Conjugate; Luteinizing Hormone-Releasing Hormone, Rhodamine-labeled; Pyro-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (Lys(Rhodamine)); Gonadorelin Rhodamine Conjugate; Rhodamine B-[Lys6]-LHRH; Fluorescent LHRH Analog; 5(6)-Carboxytetramethylrhodamine-Lys6-LHRH |
| EINECS | Contact for details |
Quality Control
Our Lhrh, Rhodamine-Lys(6)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, identity, and other critical parameters is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term stability, store under inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | Red to purple solid |
| Identification (HPLC & MS) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Single Peak Purity (HPLC) | ≥ 98% |
| Water Content (KF) | ≤ 3.0% |
| Peptide Content | ≥ 80% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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